410 research outputs found
Ab initio Quantum and ab initio Molecular Dynamics of the Dissociative Adsorption of Hydrogen on Pd(100)
The dissociative adsorption of hydrogen on Pd(100) has been studied by ab
initio quantum dynamics and ab initio molecular dynamics calculations. Treating
all hydrogen degrees of freedom as dynamical coordinates implies a high
dimensionality and requires statistical averages over thousands of
trajectories. An efficient and accurate treatment of such extensive statistics
is achieved in two steps: In a first step we evaluate the ab initio potential
energy surface (PES) and determine an analytical representation. Then, in an
independent second step dynamical calculations are performed on the analytical
representation of the PES. Thus the dissociation dynamics is investigated
without any crucial assumption except for the Born-Oppenheimer approximation
which is anyhow employed when density-functional theory calculations are
performed. The ab initio molecular dynamics is compared to detailed quantum
dynamical calculations on exactly the same ab initio PES. The occurence of
quantum oscillations in the sticking probability as a function of kinetic
energy is addressed. They turn out to be very sensitive to the symmetry of the
initial conditions. At low kinetic energies sticking is dominated by the
steering effect which is illustrated using classical trajectories. The steering
effects depends on the kinetic energy, but not on the mass of the molecules.
Zero-point effects lead to strong differences between quantum and classical
calculations of the sticking probability. The dependence of the sticking
probability on the angle of incidence is analysed; it is found to be in good
agreement with experimental data. The results show that the determination of
the potential energy surface combined with high-dimensional dynamical
calculations, in which all relevant degrees of freedon are taken into account,
leads to a detailed understanding of the dissociation dynamics of hydrogen at a
transition metal surface.Comment: 15 pages, 9 figures, subm. to Phys. Rev.
Wilson line correlators in two-dimensional noncommutative Yang-Mills theory
We study the correlator of two parallel Wilson lines in two-dimensional
noncommutative Yang-Mills theory, following two different approaches. We first
consider a perturbative expansion in the large-N limit and resum all planar
diagrams. The second approach is non-perturbative: we exploit the Morita
equivalence, mapping the two open lines on the noncommutative torus (which
eventually gets decompacted) in two closed Wilson loops winding around the dual
commutative torus. Planarity allows us to single out a suitable region of the
variables involved, where a saddle-point approximation of the general Morita
expression for the correlator can be performed. In this region the correlator
nicely compares with the perturbative result, exhibiting an exponential
increase with respect to the momentum p.Comment: 21 pages, 1 figure, typeset in JHEP style; some formulas corrected in
Sect.3, one reference added, results unchange
Classical Solutions of the TEK Model and Noncommutative Instantons in Two Dimensions
The twisted Eguchi-Kawai (TEK) model provides a non-perturbative definition
of noncommutative Yang-Mills theory: the continuum limit is approached at large
by performing suitable double scaling limits, in which non-planar
contributions are no longer suppressed. We consider here the two-dimensional
case, trying to recover within this framework the exact results recently
obtained by means of Morita equivalence. We present a rather explicit
construction of classical gauge theories on noncommutative toroidal lattice for
general topological charges. After discussing the limiting procedures to
recover the theory on the noncommutative torus and on the noncommutative plane,
we focus our attention on the classical solutions of the related TEK models. We
solve the equations of motion and we find the configurations having finite
action in the relevant double scaling limits. They can be explicitly described
in terms of twist-eaters and they exactly correspond to the instanton solutions
that are seen to dominate the partition function on the noncommutative torus.
Fluxons on the noncommutative plane are recovered as well. We also discuss how
the highly non-trivial structure of the exact partition function can emerge
from a direct matrix model computation. The quantum consistency of the TEK
formulation is eventually checked by computing Wilson loops in a particular
limit.Comment: 41 pages, JHEP3. Minor corrections, references adde
Structural and dynamical properties of superfluid helium: a density functional approach
We present a novel density functional for liquid 4He, properly accounting for
the static response function and the phonon-roton dispersion in the uniform
liquid. The functional is used to study both structural and dynamical
properties of superfluid helium in various geometries. The equilibrium
properties of the free surface, droplets and films at zero temperature are
calculated. Our predictions agree closely to the results of ab initio Monte
Carlo calculations, when available. The introduction of a phenomenological
velocity dependent interaction, which accounts for backflow effects, is
discussed. The spectrum of the elementary excitations of the free surface and
films is studied.Comment: 37 pages, REVTeX 3.0, figures on request at [email protected]
Open Wilson Lines and Group Theory of Noncommutative Yang-Mills Theory in Two Dimensions
The correlation functions of open Wilson line operators in two-dimensional
Yang-Mills theory on the noncommutative torus are computed exactly. The
correlators are expressed in two equivalent forms. An instanton expansion
involves only topological numbers of Heisenberg modules and enables extraction
of the weak-coupling limit of the gauge theory. A dual algebraic expansion
involves only group theoretic quantities, winding numbers and translational
zero modes, and enables analysis of the strong-coupling limit of the gauge
theory and the high-momentum behaviour of open Wilson lines. The dual
expressions can be interpreted physically as exact sums over contributions from
virtual electric dipole quanta.Comment: 37 pages. References adde
Localization for Yang-Mills Theory on the Fuzzy Sphere
We present a new model for Yang-Mills theory on the fuzzy sphere in which the
configuration space of gauge fields is given by a coadjoint orbit. In the
classical limit it reduces to ordinary Yang-Mills theory on the sphere. We find
all classical solutions of the gauge theory and use nonabelian localization
techniques to write the partition function entirely as a sum over local
contributions from critical points of the action, which are evaluated
explicitly. The partition function of ordinary Yang-Mills theory on the sphere
is recovered in the classical limit as a sum over instantons. We also apply
abelian localization techniques and the geometry of symmetric spaces to derive
an explicit combinatorial expression for the partition function, and compare
the two approaches. These extend the standard techniques for solving gauge
theory on the sphere to the fuzzy case in a rigorous framework.Comment: 55 pages. V2: references added; V3: minor corrections, reference
added; Final version to be published in Communications in Mathematical
Physic
On the pion-nucleon coupling constant
In view of persisting misunderstanding about the determination of the
pion-nucleon coupling constants in the Nijmegen multienergy partial-wave
analyses of pp, np, and pbar-p scattering data, we present additional
information which may clarify several points of discussion. We comment on
several recent papers addressing the issue of the pion-nucleon coupling
constant and criticizing the Nijmegen analyses.Comment: 19 pages, Nijmegen preprint THEF-NYM-92-0
The low-lying excitations of polydiacetylene
The Pariser-Parr-Pople Hamiltonian is used to calculate and identify the
nature of the low-lying vertical transition energies of polydiacetylene. The
model is solved using the density matrix renormalisation group method for a
fixed acetylenic geometry for chains of up to 102 atoms. The non-linear optical
properties of polydiacetylene are considered, which are determined by the
third-order susceptibility. The experimental 1Bu data of Giesa and Schultz are
used as the geometric model for the calculation. For short chains, the
calculated E(1Bu) agrees with the experimental value, within solvation effects
(ca. 0.3 eV). The charge gap is used to characterise bound and unbound states.
The nBu is above the charge gap and hence a continuum state; the 1Bu, 2Ag and
mAg are not and hence are bound excitons. For large chain lengths, the nBu
tends towards the charge gap as expected, strongly suggesting that the nBu is
the conduction band edge. The conduction band edge for PDA is agreed in the
literature to be ca. 3.0 eV. Accounting for the strong polarisation effects of
the medium and polaron formation gives our calculated E(nBu) ca. 3.6 eV, with
an exciton binding energy of ca. 1.0 eV. The 2Ag state is found to be above the
1Bu, which does not agree with relaxed transition experimental data. However,
this could be resolved by including explicit lattice relaxation in the Pariser-
Parr-Pople-Peierls model. Particle-hole separation data further suggest that
the 1Bu, 2Ag and mAg are bound excitons, and that the nBu is an unbound
exciton.Comment: LaTeX, 23 pages, 4 postscript tables and 8 postscript figure
Provider- and patient-level predictors of oral anticancer agent initiation and adherence in patients with metastatic renal cell carcinoma
Background: Improving oral anticancer agent (OAA) initiation and adherence is the important quality-of-care issues, particularly since one fourth of anticancer agents being developed will be administered orally. Our objective was to identify provider- and patient-level characteristics associated with OAA initiation and adherence among individuals with metastatic renal cell carcinoma (mRCC). Methods: We used state cancer registry data linked to multi-payer claims data to identify patients with mRCC diagnosed in 2004–2015. Provider data were obtained from North Carolina Health Professions Data System and the National Plan & Provider Enumeration System. We estimated risk ratios (RRs) and corresponding 95% confidence limits (CLs) using modified Poisson regression to evaluate factors associated with OAA initiation and adherence. Results: Among the 207 (out of 687) patients who initiated an OAA following mRCC diagnosis and survived 90 days, median proportion of days covered was 0.91. Patients with a modal provider specializing in hematology/medical oncology were much more likely to initiate OAAs than those seen by other specialties. Additionally, patients with a female provider were more likely to initiate OAAs than those with a male provider. Compared to patients treated by providers practicing in both urban and rural areas, patients with providers practicing solely in urban areas were more likely to initiate OAAs, after controlling for patient-level factors (RR = 1.37; 95% CL: 1.09–1.73). Medicare patients were less likely to be adherent than those with private insurance (RR = 0.61; 95% CL: 0.42–0.87). Conclusions: Our results suggest that provider- and patient-level factors influence OAA initiation in patients with mRCC but only insurance type was associated with adherence
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types
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